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CD10 - A Reliable Marker

Updated: Sep 15

Human CD10 antibody, also known as common acute lymphoblastic leukemia (CALLA), has been shown to react with TdT+ lymphoblastic leukemia, follicular germinal cell lymphoma, Burkitt’s lymphoma and chronic myelocytic leukemia. CD10 also marks normal early lymphoid progenitor cells, immature B-cells in adult bone marrow and germinal cells in normal tonsil and normal lymphoid tissue. It is also expressed in some non-lymphoid tissues such as fibroblasts, breast myoepithelium and brush border of kidney. CD10 antibody may be used in a panel for mantle cell lymphoma with Cyclin D1 (+), CD43 (+), CD5 (+), IgM (+), CD23 (-) and CD10 (-).


CD10 is also positive in pancreatic neuroendocrine tumors and almost all solid pseudopapillary tumors.


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CD10 is available in the following formats:

Format

Description

Concentrate

0.1, 0.5, 1.0 mL

Predilute

6.0 mL RTU

Q Series*– For Leica BOND-III

7 mL RTU

UltraLine* – For BenchMark

6.0 mL RTU


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A New Kind of Antibody for Your Leica Bond


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Ready to Use Antibodies for Your Roche Instrument


Visit the Biocare Medical website for more information on CD10:




*Q Seriesâ„¢ antibodies are developed solely by Biocare Medical LLC and do not imply approval or endorsement of Biocare antibodies by Leica Biosystems. Biocare and Leica Biosystems are not affiliated, associated or related in any way. Leica, Leica Biosystems, BOND-MAX and BOND-III are trademarks of Leica Biosystems.

*UltraLine antibodies are developed solely by Biocare Medical and do not imply approval or endorsement of Biocare’s antibodies by Roche® or VENTANA®.

Biocare and Roche/Ventana are not affiliated, associated or related in any way. Roche®, Ventana®, Benchmark® XT, and Benchmark® Ultra are registered trademarks of Roche.


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